The microbiota, a complex ensemble of microorganisms present in various body locations, particularly the intestines, plays a fundamental role in animal health and well-being. It directly influences digestion, immunity, and even animal behavior. Understanding and leveraging this microbial diversity has become a major challenge in improving livestock practices and animal health.
During our Microbiota Meeting on March 20, Jérôme Le Douce, Clinical Research Manager at INNOZH, presented INNOZH’s work on methods and tools dedicated to evaluating microbiota in monogastrics.
Microbiota analysis is now widely integrated into INNOZH’s research aimed at assessing the effectiveness of innovative solutions in improving animal health and performance. The presented method and tools combine INNOZH’s multidisciplinary expertise, merging veterinary skills, animal health, and animal production, to highlight the importance of microbiota, its development, and resilience, providing complementary insights into the impact of tested solutions.
Expertise and Innovation in Microbiota: INNOZH stands out with its integrated approach, combining scientific expertise and practical applications. The team’s research aims to understand and exploit microbiota variability to enhance the health and well-being of livestock animals.
Methodology and Process: INNOZH’s work relies on rigorous methodology, including precise field sampling and advanced analyses with partner laboratories. « Samples, collected from various species (pigs, poultry, etc.), are analyzed to identify bacterial populations and their interactions. This approach allows testing targeted solutions, such as probiotics and dietary supplements, tailored to the specific needs of each species, » explains Jérôme Le Douce.
Statistical Expertise: INNOZH’s statistical expertise is crucial in interpreting complex microbiota analysis data. Jérôme Le Douce continues: « Using advanced data analysis techniques, the team can detect significant trends and correlations, enabling precise recommendations for partner companies and project sponsors. »
Creation of a Metabolomic Database: « To enhance our analytical capabilities, we are developing a metabolomic database. This database will predict and identify specific biomarkers and evaluate the impact of various solutions on microbiota and the metabolites it produces. It is a valuable tool for precise diagnosis and optimizing nutritional and therapeutic strategies, » Jérôme Le Douce adds.
Applications and Results in Poultry Farming: INNOZH explores the impact of antibiotic treatments on poultry microbiota. The results show significant differences in microbial diversity between treated and untreated groups, paving the way for more sustainable and effective farming practices. Samples collected from farms include feces and intestinal portions. These samples are analyzed to assess the impact of tested solutions on microbiota, identifying pathogenic strains and quantifying bacterial populations. The results help optimize farming practices and develop innovative therapeutic solutions.
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